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 Post subject: Tramadol + Suboxone
PostPosted: Sun Jun 10, 2012 6:28 pm 
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Do they have any effect on each other either positive or negative?

I saw my counselor and all that on Friday and am seeing the Sub doc tomorrow at noon for first dose etc etc. Was prescribed Ultram (tramadol) for pain at the ER a week ago UNTIL I could get to the Sub doc.

I'm supposed to remain clean for 48 hours before my appt tomorrow. Can I still take my Tramadol? Or with that cause precipitated withdrawal?

Plz help, very uncomfortable but I don't wanna mess it up and have to wait another 48 hours...

Thanks


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PostPosted: Sun Jun 10, 2012 7:20 pm 
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There is alot of information out there about tramadol/ultram.

Some people are even perscribed it for pain, along w/suboxone.

BUT, I would think you'd still need to be in the same amount of w/d from tramadol, as anything else. Ive also heard that tramadol only works as an 'opiate' for some people, and it depends on a certain liver enzyme.

If it were me, I'd play it on the 'safe side' and be in w/d before taking suboxone.

and heres some links of info we already have here about it

"ultram...... a need to know
http://suboxforum.com/viewtopic.php?t=6 ... m+tramadol

appropriate dose for someone previosly on 700mg of ultram
http://suboxforum.com/viewtopic.php?t=6 ... dol+ultram

suboxone for tramadol
http://suboxforum.com/viewtopic.php?t=5 ... dol+ultram



This one is somebody doing the same thing as you,,,,,
and I think they DID experience some precipitated w/d,
THIS is worth read!!!!
"question of whether I took subs too early, please help" (drug oof choice, tramadol)
http://suboxforum.com/viewtopic.php?t=3 ... dol+ultram

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 Post subject: tinaburger
PostPosted: Sun Jun 10, 2012 10:24 pm 
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If you're worried about being thrown into precipitated withdrawal then don't take the tramadol. Amber is right when she says that tramadol itself is a very weak opioid and it's only due to it's active metabolite, o-desmethyltramadol that is responsible for it's weak agonist activity. A certain liver enzyme is necessary to metabolize tramadol into the active metabolite and depending on an allele that may either induce or inhibit this isozyme in the liver (Cytochrome P-450 isozyme 2D6) and either increase or decrease it's effectiveness or efficacy.

It's unfortunate but it is imperative that you are in mild to moderate withdrawal from all opioids before your induction with Suboxone (or it should be Subutex) in order to avoid a potential precipitated withdrawal experience. No pain, no game.

Good luck with your therapy and stay sober.



KeefSom

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 Post subject:
PostPosted: Mon Jun 11, 2012 10:39 pm 
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tinaburger: How did it go at your sub appt today?

I know it's probably too late, but here are a couple other threads that you might be interested in, which discuss Tramadol:

http://suboxforum.com/viewtopic.php?t=9 ... ght=ultram

http://suboxforum.com/viewtopic.php?t=6493&highlight=


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