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PostPosted: Mon Jun 11, 2012 6:35 am 
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I did a bit of reading on this today. It seems that the most studied drug in this regard of recent years has been alcohol. Fetal alcohol syndrome, it seems, can have significant long term ramifications in a child's development. Those who have fetal alcohol syndrome are found to be more prone to dependence later in life, and issues such as ADHD.

MOST of the studies about opioids that look into long term effects were done with rats. Because a study into human outcomes would take years, even decades, to uncover the full picture, most studies use rodents. While this does offer an indication and can translate to human behaviour (otherwise they wouldn't do it), it's not exactly concrete.

There are also studies comparing NAS with methadone, and general NAS outcomes.

[web]http://www.sciencedirect.com/science/article/pii/S030645300100049X[/web]

[web]http://www.sciencedirect.com/science/article/pii/037687169390032L[/web]

[web]http://www.ncbi.nlm.nih.gov/pubmed/9658424[/web]

[web]http://www.sciencedirect.com/science/article/pii/S0376871603000620[/web]

[web]http://ukpmc.ac.uk/abstract/MED/12492761[/web]

[web]http://www.sciencedirect.com/science/article/pii/S0376871608000677[/web]


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Fond Du Lac Psychiatry
Dr. Jeffrey Junig, M.D., Ph.D.

  • Board Certified Psychiatrist
  • Asst Clinical Professor, Medical College of Wisconsin

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