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PostPosted: Tue Aug 18, 2015 9:01 am 
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I wanted to post this, because from what I've found, there has been little research done on the effects of intense exercise on the metabolism of any drug, let alone on suboxone specifically.
I am a chronic gym rat-- exercise has been a lifesaver after getting clean-- it helps with mood, PAWS symptoms, gives me a routine I can stick to, goals I can strive for...the list of benefits has been endless.
But!
As my doctor has been tapering my dose of suboxone downward, I started to notice that I would go into withdrawal immediately following a bout of sustained and intense exercise. At first, when I did some research and found no known correlation, I considered the possibility that it was my imagination, or that I was attributing my symptoms to the wrong thing.
But as the taper decreased my dose further, the withdrawals after exercise increased exponentially. now, for reference, I should mention that I exercise like an athlete-- two to three hours of intense cardio daily, plus circuit training.
I started dosing right before exercising, and found that it helped a lot.
But last week, I took three days off from the gym, and when I went back, the withdrawals after exercise had increased in severity, to no small extent.
It took me a while to figure out what happened: during those three days, I was absorbing the 8mg more fully, slower, than I was on gym days, essentially increasing my dose. So when I went back, and the exercise lowered the amount of available suboxone in my bloodstream, I went into withdrawal.
Personally, I feel that there is no question as to whether prolonged and intense exercise affect suboxone kinetics and metabolism. My symptoms have been predictable, and I've systematically ruled out all other possibilities. Plus, again, dosing before the exercise helped a lot.
I wanted to share this because exercise is commonly advised to people who are in recovery. The brutal thing is that my doctor can't alter my dosing based on my exercising, because there is no literature, no studies, no guidelines regarding how to allow for this variable. From now on, I won't be taking my full dose on my off days, because I'm positive that exercise decreases the amount of suboxone in my system. It would be interesting to hear if anyone else is a chronic exerciser and has noticed symptoms afterward, and I'd be very interested to hear what the doctor himself may have to say. Peace


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PostPosted: Tue Aug 18, 2015 4:50 pm 
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Welcome to our forum! Your hypothesis, although based on anecdotal information, makes a lot of sense!

One thing I learned in psychopharmacology is that it's incredibly difficult for even professionals to understand the complex mechanisms within the body that produce a drug's effect. Metabolism is part of the mystery for sure.

Amy

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PostPosted: Sat Aug 22, 2015 6:36 pm 
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I'm going to have to agree with your theory. I notice that when I'm doing more intense work the suboxone work really well during the work, but then after have the feeling of needing more. It's like the medicine over works itself with my body then wears itself out! Crazy, but there should be some studies on this and what happens to the levels in a person's body after intense workouts. This would be very interesting to see the results!


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Fond Du Lac Psychiatry
Dr. Jeffrey Junig, M.D., Ph.D.

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