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PostPosted: Sat Jul 28, 2012 9:25 pm 
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I have been told by Gyn to start large quantities of Calcium, Vitamin D3, Magnesium & Gloucosamine. But I see CALCIUM as a blocker on some sites. Will it cause withdrawal? I am confused.


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PostPosted: Sat Jul 28, 2012 11:01 pm 
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Hi EP33L,

I've never heard of Calcium as a blocker of opiates, so I looked it up real quick and I think what you're seeing about Calcium is that it's a depotentiator (decreases the effects of) opiates. To the best of my knowledge, Calcium will not throw you into wd, what it will do is decrease the euphoric effects of an opiate.....I think?

To be thrown into wd, you would need a chemical to enter the brain and knock all your Suboxone off your opiate receptors, I honestly don't believe Calcium is capable of that.

I drank plenty of milk while I was on opiates, including Suboxone and it never threw me into wd.

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 Post subject: PHEW
PostPosted: Sat Jul 28, 2012 11:54 pm 
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Thank you so much. It can be confusing with meds ... u know u spend 15 minutes with a doctor. He gives you a script. Takes $150 & tells u to read the info pamphlet. The Pharmacist gives me a dirty look if I have a question & tells me to ask my doc. I call him up & leave 33 msg.
I thank you AGAIN because this site has been very informative to me. I am relieved.
:)

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PostPosted: Sun Jul 29, 2012 7:29 am 
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EP33L - I personally haven't heard of calcium having an effect on Suboxone before. I checked the list of inhibitors and inducers of the CYP3A4 enzyme, which is the enzyme that metabolizes buprenorphine, and it is not listed. Any drug or supplement that is on the Inhibitors list has been shown to speed up metabolism of buprenorphine, possibly resulting in having withdrawal symptoms earlier than normal. Any medications/supplements on the list of Inducers are known to slow down metabolism of sub, which would do the opposite. Here is the list in case you would like to review it for yourself:

INHIBITORS
amlodipine
boceprevir
cimetidine
ciprofloxacin
danazol
dronedarone
ethinyl estradiol
everolimus
kava
marijuana
methyl-prednisolone
mifepristone
nefazodone
nicardipine
nifedipine
nilotinib
norfloxacin
pomegranate
pazopanib
prednisone
propoxyphene
quinine
ranolazine
synercid
telaprevir
tipranavir
zafirlukast

INDUCERS
amprenavir
aprepitant
ethosuximide
etravirine
garlic supplements
glucocorticoids
glutethimide
ritonavir


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