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PostPosted: Mon Mar 23, 2015 4:55 pm 
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I came across this reference to a new study published in the American Journal of Psychiatry. The study concludes that clonidine prescribed in conjunction with buprenorphine can enhance the effectiveness of buprenorphine for opiate addicts.

This could be especially significant (I imagine) to those of us who take a lower dose of bupe. It may be that patients could take lower doses of bupe comfortably if also taking clonidine. We already know that clonidine is an effective symptom reliever during withdrawal. Maybe the combination could help those who wish to be on an effective but low dose of bupe for financial or other reasons.

Has anyone's doctor brought up this study or prescribed you the two drugs simultaneously?

Amy

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PostPosted: Mon Mar 23, 2015 11:37 pm 
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Amy, I looked at the latest issue and couldn't find the article. Do you have the reference?

Clonidine was studied for treating chronic pain back when I was doing anesthesia. There was some hope that it could be used in epidurals or spinals, to provide pain relief during labor without causing numbness or weakness... but it caused too much hypotension (low blood pressure) to be useful in that population. There are clearly interactions between opioids and adrenergic neurotransmitters, where clonidine has an action...

Post the link if you have it-- thanks!


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PostPosted: Tue Mar 24, 2015 12:37 am 
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I saw it at NIDA. Here's the link: http://www.drugabuse.gov/news-events/ne ... it-success

Amy

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