It is currently Thu Jan 18, 2018 8:02 am

All times are UTC - 5 hours [ DST ]

Our Sponsors

Post new topic Reply to topic  [ 5 posts ] 
Author Message
PostPosted: Tue Dec 14, 2010 8:31 am 
New Poster
New Poster

Joined: Tue Dec 14, 2010 7:59 am
Posts: 1
I was on Buprenorphine for over five years. I tried many methods trying to get off of it when I deemed I no longer needed it. I tried cold turkey, accupuncture, hypnosis and weaning to extremely low doses. I was always doing research. I am also a recovering alcoholic.

My therapist knew of my struggle and asked me to read a book he had recently obtained. It was called The End of My Addiction, by Dr. Oliver Ameisen. Dr. Ameisen was a severe alcoholic who discovered that Baclofen cured him of his desire to use alcohol. In his book, he also stated that he thought Baclofen could be used for other addictions as well. My heart did a little jump!

I started researching Baclofen which was being used frequently in Europe. I compiled my research and took it to my physician. He agreed to let me try it the same way in which Dr. Ameisen used it. After finally resting on a dose that was comfortable, I started testing myself to see how long I could comfortably go without a dose. I was only on 1/2 mg/day. I was able to stretch it out for two to two and a half days. Then I began to have restless leg syndrome severely. That was my only complaint but one I can't stand. There was no upset stomach, no diarrhea, no shakes... only restless leg.

I went back to my physician and told him the problem and asked him if he could put me on Mirapex. My therapist used it for severe chronic restless leg and said it worked wonders. My physician wrote me a script and I started taking it. Two days after starting it, I took myself off of Buprenorphine. I felt really tired but I believe I was overusing my Clonidine which my psychiatrist had prescribed for anxiety. I quit taking the Clonidine and within 24 hours, I felt much better.

The only problem that I am having is being extremely tired. It seems to be good one day, then terrible the next. But, I haven't had any Buprenorphine in almost a month. I am ecstatic about being off of the Bupe. :D :D

Last edited by snap_knight on Tue Dec 14, 2010 8:48 am, edited 1 time in total.

 Post subject:
PostPosted: Tue Dec 14, 2010 8:39 am 
Long Time Member
Long Time Member
User avatar

Joined: Wed Apr 29, 2009 12:55 pm
Posts: 4847
Location: Leesburg, FL
Hello snap and welcome to the forum. Congratulations! It sounds like your plan worked like a charm. That's terrific! I personally don't know anything about Baclofen, so maybe you could tell us more about it - what it is, how it works, etc. Again, congratulations and good luck on your continued recovery/remission.

-As I have grown older, I've learned that pleasing everyone is impossible, but pissing everyone off is a piece of cake.

-I'm only responsible for what I say, not for what you understand.

PostPosted: Wed Dec 15, 2010 12:05 pm 
Super-Duper Poster
Super-Duper Poster

Joined: Thu Nov 25, 2010 6:39 pm
Posts: 311
Hi Snap,
Wow, what a great job! i am impressed by how you did the footwork, compiled the research, organizing and bringing it to your physician who was open to hearing new treatments. That is fantastic and how things SHOULD work I believe! We educate ourselves....not go blindly along with what the "doctor" says....I'm happy for you. Freedom in many ways!

I had a client, a very chronic relapsing alcoholic, a professional woman who ended up losing everything to her disease. She had been in 11 treatments when she came to me. She had remarried again and was on the verge of losing this marriage, one she was very committed to and she was terrified. She felt unable to remain in recovery due to her continual cravings for alcohol. She tried various treatments both medical and homeopathic. Nothing helped her. She exercised, ate well, did acupuncture, hypnosis..AA, Smart name it. She even tried Antabuse. Yuck.

She completed my program and was doing well...but still having cravings. This woman did NOT have another recovery in her and she believed that it would be the end if she didn't get some relief. Talk about suffering. My heart just hurt for her.
At the end of her treatment she called me and said she read a book. the same one as you did. She brought it in and we did some research and I said go for it. So we put together the information for her PCP and she wrote her the rx.

About a month later she called me to say that she had never felt better. That her cravings were completely gone and she was still sober, something that had not ever been possible for her. 4 months later she called again...same thing.

that is my only experience wtih baclofen but I have also read that it might be useful for other craving or withdrawal symptoms....

It's great to hear how it worked for you.

Our Sponsors
 Post subject:
PostPosted: Wed Dec 15, 2010 9:27 pm 
Long Time Member
Long Time Member
User avatar

Joined: Wed Feb 17, 2010 10:03 pm
Posts: 991
From Wikipedia, the free encyclopediaJump to: navigation, search
1 : 1 mixture (racemate)
Systematic (IUPAC) name
(RS)-4-amino-3-(4-chlorophenyl)butanoic acid
CAS number 1134-47-0
ATC code M03BX01
PubChem CID 2284
IUPHAR ligand 1084
DrugBank APRD00551
ChemSpider 2197 Y
Chemical data
Formula C10H12ClNO2
Mol. mass 213.661 g/mol
SMILES eMolecules & PubChem
InChI[show]InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) Y
Pharmacokinetic data
Bioavailability well absorbed
Protein binding 30%
Metabolism 85% excreted in urine/faeces unchanged. 15% metabolised by deamination
Half-life 1.5 to 4 hours
Excretion renal (70-80%)
Therapeutic considerations
Pregnancy cat. C(US)
Legal status ?
Routes Oral, intrathecal
Y(what is this?) (verify)

Baclofen (brand names Kemstro and Lioresal) is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is under investigation for the treatment of alcoholism.

It is an agonist for the GABAB receptors.[1][2] Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups, and has been shown to prevent rises in body temperature induced by the drug MDMA in rats.[3]

In addition, research over the last five years has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.[4][5]

A very beneficial property of baclofen is that tolerance does not seem to occur to any significant degree — baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use.[6] However, oral dosage must be carefully regulated; significantly high doses of the drug, particularly 80 milligrams per day or higher, can cause excessive drowsiness that can interfere with daily function.

Contents [hide]
1 Use
2 Mechanism of action
3 History
3.1 As a treatment for alcohol and other addictions
4 Description of compound
5 Pharmacokinetics
6 Routes of administration
7 Dosage
8 Withdrawal syndrome
9 Overdose
10 References
11 External links

[edit] Use
Baclofen is widely used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, spastic diplegia cerebral palsy, multiple sclerosis, amyotrophic lateral sclerosis (Lou Gehrig's disease), peripheral neuropathy and trigeminal and glossopharyngeal neuralgias.[citation needed]

Baclofen is often the primary, or at least preliminary, drug treatment for spastic diplegia and more general spasticity-based mobility impairments. Research has not, however, shown it to be consistently effective in improving function for people with these issues.[7][8] Sometimes, effects are immediate and clear; other times, effects may be mild, vague, or nonexistent. What is known for sure is that, for unknown reasons, in about 5% of the spastic cerebral palsy people who try intrathecally-administered baclofen, the drug has no effect whatsoever on the person's spasticity. It does appear that intrathecal baclofen may be more effective than oral baclofen, but some believe the long-term risks of an intrathecal pump (allegedly including sudden infection, sudden malfunction leading to coma and death, etc.) are so severe that many clinicians and/or patients choose not to administer baclofen intrathecally at all. Most specialists and manufacturers of intrathecal pumps strongly disagree with the belief that an intrathecal pump carries with it a significant or even remote risk of serious complication. A pump that fails, shuts down. Inthatecal pumps are much more commonly used for the delivery of morphine than baclofen alone (although a mixture of both for chronic pain sufferers is common}. A failure of the type alleged with an intrathecal pump with morphine would be fatal if it occurred when the pump was full or near to full where even a small amount suddenly was released into the Cerebral Spinal Fluid. It would likel be fatal if released into the abdominal cavity.

The chance of an intrathecal pump failing resulting in overdosing other than by human error seems to be so low that no record of such a failure could be found. Inthrathecal pumps do fail. Air can be introduced into the pump (extrmely rare with the result being the non delivery of the medication). Sometimes medical practitioners mistake the programming and this has resulted in an overdose potentially life threatening on at least one occasion.

Baclofen has been shown to be as effective as diazepam in uncomplicated alcohol withdrawal syndrome.[4] An Italian study showed that it was effective in promoting alcohol abstinence in patients with severe liver cirrhosis.[9]

[edit] Mechanism of action
Baclofen produces its effects by modulating the GABAB receptor, similar to the drug GHB which also activates this receptor and shares some of its effects. However, baclofen does not have significant affinity for the GHB receptor, and has no known abuse potential.[10][11] The modulation of the GABAB receptor is what produces baclofen's range of therapeutic properties.

Criticism may not be agreeable, but it is necessary. It fulfills the same function as pain in the human body. It calls attention to an unhealthy state of things.

- Winston Churchill

 Post subject: another option
PostPosted: Sat Dec 25, 2010 7:42 am 
Power Poster
Power Poster
User avatar

Joined: Wed May 20, 2009 6:04 pm
Posts: 73
when I was going the 3 days between the fent patches and LDN, I had horrible back pain and rls and my dr wrote me baclofen. did not work well and he wrote me parafon Forte 500 mg which is also non addictive, but worked much better for ME. just another option and tool to help people in whatever their quest!

"If I am not for me, who will be for me?"

"To have self esteem, one must do esteemable acts"

Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 5 posts ] 

All times are UTC - 5 hours [ DST ]

Who is online

Users browsing this forum: No registered users and 0 guests

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Search for:
Jump to:  
Our Sponsors
Suboxone Forum latest topics RSS feed Subscribe to the entire forum


Fond Du Lac Psychiatry
Dr. Jeffrey Junig, M.D., Ph.D.

  • Board Certified Psychiatrist
  • Asst Clinical Professor, Medical College of Wisconsin

Powered by phpBB® Forum Software © phpBB Group